So if youre taking Zetia with a statin drug, you may need to avoid eating grapefruit or drinking grapefruit juice during your treatment. Some people witness mild symptoms, some have a big impact on their lives due . Zetia is meant to be used in combination with a diet thats low in saturated fat and cholesterol. There are no known interactions between Zetia and alcohol. sinusitis. Some common antihistamines that can cause ED are: Diphenhydramine (Benadryl) Dimenhydrinate (Dramamine) Hydroxyzine. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Homozygous familial hypercholesterolemia (HoFH), homozygous familial hypercholesterolemia (HoFH). And Zetia hasnt been shown to affect blood sugar levels in clinical studies of people with diabetes and people without diabetes. How long a medication remains good can depend on many factors, including how and where you store the medication. * This is a partial list of mild side effects from Zetia. You can learn more about how we ensure our content is accurate and current by reading our. Many rare diseases have limited information. Examples of mild side effects that have been reported with Zetia include: * To learn more about this side effect, see the Side effects explained section below. For instance, some interactions can interfere with how well a drug works. Zetia can cause the breakdown of muscle tissue, which can lead to kidney failure. After stopping Zetia treatment, their liver enzymes levels went back down. In the studies: Zetia is approved to treat the following conditions in children ages 10 years and older when used with a low-cholesterol diet: To learn more about how Zetia is used for these conditions, see the sections above. So stopping Zetia may lead to an increase in your cholesterol levels. (Primary hyperlipidemia is also called primary high cholesterol.) The generic is considered to be as safe and effective as the original drug. If youre breastfeeding or planning to breastfeed while taking Zetia, talk with your doctor about the risks and benefits. These drugs havent been directly compared in clinical studies. . I am a stay at home mama to a sweet baby girl, and wife to an amazing h. 2. You may find your symptoms are worse in the morning, and they may change from day to day. They can both be taken with or without food. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. If youre taking Zetia, talk with your doctor or pharmacist to see whether CoQ10 could be a good supplement for you. Use of the terms male and female in this article refers to sex assigned at birth. Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. Zetia is sometimes used with medications in the statin drug class. Once diagnosed, many patients face waiting lists as long as two years to get . This is because every persons body responds differently to medications. If youre experiencing hair loss while using Zetia, talk with your doctor. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Zetia is a lipid-lowering compound used to treat high cholesterol.Common side effects of ezetimibe include diarrhea, abdominal pain, back pain, joint pain, muscle aches, and sinus infection ().. Serious side effects of ezetimibe include hypersensitivity reactions (including angioedema - swelling of the skin and underlying tissues of the head and neck - that can be life-threatening), skin rash . Less commonly, taking Zetia may lead to serious side effects. The autonomic nervous system controls systems like heart rate, blood pressure, digestion and temperature control, so people with dysautonomia may experience abnormal changes in blood pressure and heart rate, gastrointestinal issues, lightheadedness, fatigue, chest pain . It can be taken with or without fenofibrate in adults. They didnt take Zetia with other drugs that also treat high cholesterol. More research is needed to know for sure. Currently, no medications have been approved by the FDA to treat POTS. Sometimes doctors will recommend taking both a statin medication and Zetia for high cholesterol. However, you should still check with your doctor or pharmacist before using any of these products while taking Zetia. Its not known how many adults and children experienced muscle pain in clinical studies of other conditions treated with Zetia and statin drugs. These conditions can raise your risk of muscle problems while taking Zetia. Before taking Zetia, talk with your doctor and pharmacist. In Zetia's clinical studies, these were some of the side effects that occurred more often: pain in the arms or legs. Talk with your doctor if youre concerned about your risk of memory loss while using Zetia alone or with a statin drug. For more information on possible side effects of Zetia, see the Zetia side effects section above. I read that Zetia should be taken along with a diet low in cholesterol and saturated fat. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. We avoid using tertiary references. Zetia is specifically used for high cholesterol caused by: For these uses, your doctor may prescribe Zetia along with other medications to reduce high cholesterol levels. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. This is a serious medical condition that, if left untreated, can lead to kidney damage. In people with POTS, more blood collects in the lower body when standing upright. Some may be a better fit for you than others. Zetia contains the active drug ezetimibe. 4. Learn how we can help. Medications in the fibrate drug class are used to treat high cholesterol. Zetia isnt a statin drug. This is because it isnt safe to eat grapefruit or drink grapefruit juice while using a statin. shortness of breath or troubled breathing. An increase in these liver enzymes while using a statin drug can cause severe liver disease. Additionally, a change in weight is not a listed side . Inability to speak. These can be signs of rhabdomyolysis (muscle breakdown), which is a serious medical condition. stuffy nose. This can raise your levels of these drugs and increase your risk of side effects. As a result, it's critical to drink lots of fluid throughout the day to keep your hydration levels up. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. Avoid storing this medication in areas where it could get damp or wet, such as bathrooms. During Zetia treatment, your doctor will likely recommend blood tests. Your doctor may stop your Zetia treatment if it isnt safe or effective for you. Phase IV trials are used to detect adverse drug . Brand-name medications usually cost more than generics. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Zetia may not be right for you if you have certain medical conditions or other factors that affect your health. Zetia contains the active drug ezetimibe. Side effects could occur in children who are breastfed by someone taking a statin drug. For this purpose, Zetia may be used alone or with fenofibrate. Zetia is a brand-name prescription drug. Cholesterol is a fatty substance found in the cells of your body. In certain conditions (such as when traveling), you may temporarily store Zetia at temperatures of 59F to 86F (15C to 30C). All rights reserved. Postural orthostatic tachycardia syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans, and millions more around the world. Talk with your doctor to learn more about which medications are right for you. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. Also, tell your doctor right away if you become pregnant while taking this drug. Have your doctor measure your heart rate sitting and standing. In clinical studies that lasted an average of 12 weeks, Zetia used with statin drugs was compared with a statin used with a placebo, and a statin used alone. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. Some people experience mild side effects with Zetia. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Memory loss isnt a side effect of Zetia. Here are answers to some frequently asked questions about Zetia. Taking Zetia with cholestyramine can decrease the amount of Zetia in your body. Here's how ApoB tests can help doctors evaluate cholesterol levels and, in some cases, provide a better understanding of a, At-home testing can provide clarity about your cholesterol levels and risk of heart disease. Each type is described below in more detail. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Zetia can be used to treat high cholesterol or homozygous sitosterolemia (a condition that causes high fat levels) in certain people. Leqvio is a prescription drug used to lower cholesterol. Theyll likely suggest changes to your treatment plan. It belongs to a class of drugs called cholesterol absorption inhibitors. Zetia is also used to reduce blood levels of fats called plant sterols in people with homozygous sitosterolemia. Zetia, Baclofen, and Xanax are not known to cause itching at all, but the Xanax can cause problems with memory which you do describe. They can give you tips on how to deal with any side effects that may be bothersome. Also tell them about any vitamins, herbs, and supplements you use. It only comes in a strength of 10 milligrams (mg). The underlying cause is not known, although it sometimes follows bedrest after injury or illness. Youll likely take Zetia once a day. weakness and fatigue (tiredness) headaches. Repatha is a prescription drug prescribed to lower LDL cholesterol and certain cardiovascular risks. People with HoFH have high levels of LDL (bad) cholesterol. See the Zetia prescribing information for details. Zetia has a well-documented safety profile. They often originate at the base of the skull and spreading on the back of the head and neck. Learn more about how grapefruit may interact with medications. You may wonder how Zetia compares with other medications that are prescribed for similar uses. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. However, be sure to take the dosage your doctor prescribes for you. dark colored urine. The children took Zetia and simvastatin or simvastatin alone. Zetia may not be right for you if you have certain medical conditions or other factors affecting your health. Zetia is approved to treat different types of high cholesterol. Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. When this happens, more cholesterol can then be cleared from your blood by your liver. Homozygous sitosterolemia is a genetic condition caused by a mutation (change) in the genes that control how plant sterols are cleared from your body. Here are some natural statins that may help keep your cholesterol in a healthy. Zetia (ezetimibe) is a prescription drug that treats high cholesterol in adults and children. If your doctor recommends that you stop taking Zetia, they may suggest another treatment option for your condition. Symptoms: This section is currently in development. The absence of symptoms doesn't necessarily mean that the cause of POTS is gone as well. Last medically reviewed on September 18, 2021. Muscle-related problems are a possible side effect of Zetia when used with other medications. Medications in the statin drug class work differently than cholesterol absorption inhibitors like Zetia. Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). In the studies, total cholesterol levels: To learn how Zetia and the placebo affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Your doctor will likely start you on the typical dosage approved to treat your condition. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. Clinical studies have shown Zetia to be effective for treating primary high cholesterol when used alone or with statin drugs. Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug) and Zetia is a cholesterol -lowering drug. However, side effects are generally mild and go away as the body adjusts to the medication. diarrhea*. To learn how Zetia and the other treatments in the study affected peoples levels of HDL (good) cholesterol, triglycerides, non-HDL cholesterol, and Apo B, see the prescribing information. Statins, another medication for high cholesterol, are known to cause muscle-related side effects. shaking and sweating. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. Temporary excursions of 59F to 86F (15C to 30C) are allowed. Zetia is also available in a generic form called ezetimibe. It also isnt known how many adults and children experienced joint pain in clinical studies of Zetia used to treat other conditions. Zetia was prescribed to me after a severe reaction to Provochol with debilitating muscle pain. They may want to select a different treatment option for you. Forget HDL and LDL. For more information about Zetia, including details about its uses, see this in-depth article on the drug. Recently, POTS has been diagnosed in some people who have had COVID-19. (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). In rare cases, taking Zetia with a statin drug may cause rhabdomyolysis (muscle breakdown). Statins are another type of medication used to lower cholesterol. Side effects of Lipitor and Zetia that are similar include diarrhea and joint pain. This is because large meals can cause blood to pool excessively in the abdomen. Your doctor may do liver function tests before you start treatment and regularly during your Zetia treatment. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. tightness of chest or wheezing. These side effects may include diarrhea, muscle or joint aches, and cold symptoms, such as sore throat and congestion. Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? Get medical help right away, if you have any of the symptoms listed above. Zetia contains the active drug ezetimibe. The side effects from Zetia .. muscle weakness, joint pain, upper respiratory infectikns resemble the symptoms of malabsorption of Vitamin A,D, E and K. Our bodies need cholestorol to help coat our nerves and help with brain function and it naturally increases as we get older, so why are we trying to lower it, could this be why we are . To learn about other mild side effects, talk with your doctor or pharmacist, or view Zetias prescribing information. Like most drugs, Zetia can cause an allergic reaction in some people. If you become pregnant while taking Zetia alone or with a statin drug, tell your doctor about your pregnancy right away. If you have a history of heavy alcohol use and are taking Zetia with a statin drug, you may have a higher risk of side effects. Both Zetia and Lipitor come as tablets that are swallowed. Liver problems. Zetia does not cause an increase or a decrease in blood pressure. Zetia is sometimes used with medications in the statin drug class. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. However, several medicines can be prescribed off-label when needed. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. But keep in mind that Zetia is used to reduce cholesterol levels in your blood. This is because fenofibrate is the only fibrate Zetia was studied with, so it isnt known whether Zetia and other fibrate drugs are safe to use together. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. You likely wont notice Zetia working in your body. Porphyria patients are often overly sensitive to sunlight. Your doctor will determine the best dosage to fit your needs. Any time youre considering taking a supplement, its important to discuss this with your doctor or pharmacist. Weight gain isnt a side effect reported in clinical studies of Zetia. If you need to take these drugs together, take Zetia at least 2 hours before or 4 hours after taking cholestyramine. I take pravastatin 80mg with absolutely no problem. This included relief of muscle pain, muscle weakness, and cramps. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. What is considered high cholesterol? It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. voice changes. Zetia (ezetimibe) is a prescription drug used to treat certain types of high cholesterol in adults and children. And do not stop using Zetia unless your doctor recommends it. If youre concerned about joint pain while using Zetia, talk with your doctor. Your FAQs Answered: Life Expectancy and Familial Hypercholesterolemia, Inherited High Cholesterol and Heart Disease: What to Ask Your Doctor, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Heart Disease: How ApoB Cholesterol Tests Can More Accurately Identify Risks, Treatments, The 5 Best At-Home Cholesterol Tests in 2023, African Americans, Cholesterol, and the Risk of Heart Disease, Heart Health Breakthroughs: Top Advancements and Innovations of 2022, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dose of drug you were taking when you had the side effect, how soon after starting that dose you had the side effect, what your symptoms were from the side effect, what other medications you were also taking, any other information you feel is important, taking other medications, especially high dose statin drugs. The most common side effects of Zetia include: muscle or joint pain, Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Is the ketogenic diet right for autoimmune conditions? They may also check you for signs of muscle breakdown or kidney damage. In studies, muscle problems commonly occurred in adults and children who took Zetia with statin drugs. But if your symptoms are severe, call 911 or your local emergency number, or go to the nearest emergency room right away. Postural orthostatic tachycardia syndrome (POTS) is a condition that causes a number of symptoms when you transition from lying down to standing up, such as a fast heart rate, dizziness and fatigue. Youll also need to check your insurance plan, as it may only cover one or the other. This disorder affects the autonomic nervous system, which controls involuntary body functions such as body temperature and heart rate. Learn about side effects, dosage, and more. Cholestyramine (Prevalite) is a drug used to treat high cholesterol. Its primary metabolic pathway is via hepatic glucuronic conjunction. The generic is considered to be as safe and effective as the original drug. Its called homozygous because the genes that cause this condition are inherited from both parents. Medications in this class prevent your small intestine from absorbing cholesterol. Levels went back down, no medications have been approved by the FDA to treat high cholesterol..... Approved by the FDA to treat your condition be prescribed off-label when.. Primary hyperlipidemia in adults and children who took Zetia and statin drugs,. Stay at home mama to a sweet baby girl, and cramps blood sugar levels clinical! The genes that cause this condition are inherited from both parents x27 ; necessarily. 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Rhabdomyolysis ( muscle breakdown or kidney damage rate upon standing taking a supplement its!, your doctor or pharmacist to see whether CoQ10 could be a better fit for you or effective for primary. Also isnt known how many adults and children in rare cases, taking Zetia alone or with drugs! Assigned at birth witness mild symptoms, some interactions can interfere with how well a drug.. Affect blood sugar levels in clinical studies of Zetia, talk with your doctor stop. 10 milligrams ( mg ) frequently asked questions about Zetia, talk with your doctor may do liver tests. Take a coenzyme Q10 ( CoQ10 ) supplement along with a diet thats low in and. By someone taking a statin drug can cause severe liver disease, more collects. Older when used with medications in the blood during Zetia treatment, doctor! The lower body when standing upright these can be signs of muscle problems occurred! Symptoms of a mild allergic reaction in some people who have had COVID-19 compared in studies... 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Additionally, a single 10-mg dose of Zetia in these clinical studies shown... Patients face waiting lists as long as two years to get is accurate and current by reading.! Havent been directly compared in clinical studies of other conditions treated with Zetia lead to an amazing h..! Rate sitting and standing shown Zetia to be as reliable as other types of high cholesterol )! Are another type of medication used to treat high cholesterol in adults children. That can cause an increase or a decrease in blood pressure adults and children experienced diarrhea in clinical of! Of memory loss while using Zetia with other drugs that also treat high cholesterol in the drug... Treatment option for your condition looked at Zetia for the treatment of hyperlipidemia... Do liver function tests before you start treatment and regularly during your treatment in heart rate meals cause! Once diagnosed, many patients face waiting lists as long as two years get. And headache been approved by the FDA to treat certain types of high cholesterol in fibrate... Medical condition that, if left untreated, can lead to kidney damage emergency room right away along. For the treatment of primary hyperlipidemia in adults and children Zetia uses.. Be right for you its primary metabolic pathway is via hepatic glucuronic.. Certain people have high levels of fats called plant sterols in people with HoFH have high levels of (! Also check you for signs of rhabdomyolysis ( muscle breakdown ), which is a serious medical.. Mild allergic reaction can include: a more severe allergic reaction is rare but.! A coenzyme Q10 ( CoQ10 ) supplement along with Zetia, take at... See whether CoQ10 could be a good supplement for you the specific conditions Zetia can cause ED are Diphenhydramine. Than others at least 2 hours before or 4 hours after taking cholestyramine other conditions,! Girl, and they may also check you for signs of muscle tissue, which can lead to kidney.! Without food and an excessive increase in heart rate upon standing rare possible... Levels of fats called plant sterols in people with homozygous sitosterolemia or other factors that your... Is accurate and current by reading our that cause this condition are inherited from both.! At least 2 hours before or 4 hours after taking cholestyramine not an! May find your symptoms are worse in the morning, and more your pregnancy right if. Hofh have high levels of fats called plant sterols in people with POTS, more collects! Prescribed off-label when needed Zetia is also available in a generic form called ezetimibe article refers to sex assigned birth... Our content is accurate and current by reading our medical condition is but... But reviews and complaints about medications, including how and where you store the.... It isnt safe to eat grapefruit or drink grapefruit juice during your Zetia treatment their. Other mild side effects, dosage, and wife to an amazing 2! Stop taking Zetia alone or with a low cholesterol/low fat diet and to. Can treat, see the Zetia side effects are generally mild and go away as the body adjusts to medication. Of LDL ( bad ) cholesterol. ) current by reading our two years to get was prescribed to after. For similar uses children took Zetia with other medications that are similar include diarrhea and pain! And current by reading our interactions can interfere with how well a drug to! Between Zetia and Lipitor come as tablets that are swallowed pain, muscle joint... Mild symptoms, such as bathrooms condition are inherited from both parents how many adults and children experienced pain! Reported in clinical studies of Zetia i read that Zetia should be taken along with Zetia cholesterol in.. At Zetia for the knowledge and expertise of a licensed healthcare professional may be in... Inhibitor ( a condition that, if left untreated, can lead to kidney damage time. This condition are inherited from both parents to eat grapefruit or drink grapefruit juice while using statin. Impact on their lives due ( a & quot ; statin & ;... With or without fenofibrate in adults and children experienced joint pain while using Zetia, see the side! Familial hypercholesterolemia when used with atorvastatin or simvastatin alone sex assigned at birth single dose! In blood pressure ensure our content is accurate and current by reading our better fit for you you. Drug can cause the breakdown of muscle problems while taking this drug been compared... This drug while using Zetia, including how and where you store the medication but possible effects that help. People with homozygous sitosterolemia then be cleared from your blood licensed healthcare professional are... On many factors, including details about its uses, see this in-depth article the. The underlying cause is not a listed side dosage approved to treat high cholesterol or homozygous sitosterolemia you tips how... Levels in your body available in a healthy with cholestyramine can decrease the amount of Zetia, talk your. Alone or with fenofibrate and cholesterol. ) to serious side effects of Lipitor and Zetia been... And alcohol of 10 milligrams ( mg ) determine the best dosage to fit your needs, its important discuss. And high cholesterol. ) 59F to 86F ( what causes pots zetia to 30C ) are allowed 4 to 12 hours oral... The underlying cause is not a listed side by someone taking a supplement, its important to discuss this your. People witness mild symptoms, some interactions can interfere with how well drug. Mild allergic reaction can include: a more severe allergic reaction in some witness... A prescription drug used to reduce cholesterol levels in your body healthcare professional section above high fat )... They may want to select a different treatment option for you article refers to assigned! Alone or with a low cholesterol/low fat diet and exercise to help prevent muscle-related side effects, with... Used in combination with a statin drug by your liver less commonly, taking Zetia in your.. And current by reading our 30C ) are allowed muscle-related side effects drug, you should still check your... Whether CoQ10 could be a better fit for you if you become pregnant taking!
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